Host: Rabbit

Target Protein: FEM 1B

IR: Immunogen Range:531-627/627

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10116

Swiss Prot: Q9UK73

Source: KLH conjugated synthetic peptide derived from human FEM 1B:531-627/627 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
Tissue specificity: Widely expressed. Highly expressed in testis. Weakly expressed in other tissues.