Host: Rabbit

Target Protein: TSPYL5

IR: Immunogen Range:251-350/417

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 85453

Swiss Prot: Q86VY4

Source: KLH conjugated synthetic peptide derived from human TSPYL5:251-350/417 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.