Host: Rabbit
Target Protein: UBE2V1
IR: Immunogen Range:51-147/147
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 387522
Swiss Prot: Q13404
Source: KLH conjugated synthetic peptide derived from human UBE2V1:51-147/147
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Size: 200ul
Concentration: 1mg/ml
Applications: IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=2ug/Test, ELISA=1:5000-10000
Cross Reactive Species: Human,Rat (predicted: Mouse,Chicken,Pig,Horse,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.