Host: Rabbit
Target Protein: ENC1
IR: Immunogen Range:241-300/589
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 8507
Swiss Prot: O14682
Source: KLH conjugated synthetic peptide derived from human ENC1:241-300/589
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:
Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. May be down-regulated in neuroblastoma tumors. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Tissue specificity:
Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas.
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=0.2ug/test, ELISA=1:5000-10000
Cross Reactive Species: Rat,Mouse,Human (predicted: Sheep,Rabbit,Horse,Cow)
For research use only. Not intended for diagnostic or therapeutic use.