bs-0412R [Primary Antibody]
Rabbit  Anti-MMP2  Polyclonal Antibody
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Host: Rabbit

Target Protein: MMP2

IR: Immunogen Range:31-109/476

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4313

Swiss Prot: P08253

Source: KLH conjugated synthetic peptide derived from human MMP2:31-109/476 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Size: 50ul

Concentration: 1mg/ml

Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1μg/Test, ELISA=1:5000-10000

Cross Reactive Species: Human,Mouse,Rat (predicted: Chicken,Pig,Cow,Rabbit,Sheep)

For research use only. Not intended for diagnostic or therapeutic use.

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