Host: Rabbit

Target Protein: Unc18-3

IR: Immunogen Range:165-260/592

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6814

Swiss Prot: O00186

Source: KLH conjugated synthetic peptide derived from human Unc18-3:165-260/592 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.