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Host: Rabbit
Target Protein: AMPK alpha 1
IR: Immunogen Range:351-450/559
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 5562
Swiss Prot: Q13131
Source: KLH conjugated synthetic peptide derived from human AMPK alpha 1:351-450/559
Purification: affinity purified by Protein G
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:200-1000, IHC-P=1:100-500, IHC-F=1:100-500, Flow-Cyt=1ug/Test
Cross Reactive Species: Human,Mouse,Rat (predicted: Chicken,Dog,Pig,Cow,Horse)
For research use only. Not intended for diagnostic or therapeutic use.