Host: Rabbit

Target Protein: phospho-FSCN1 (Ser39)

IR: Immunogen Range:AS(p-S)LK

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6624

Swiss Prot: Q16658

Source: KLH conjugated Synthesised phosphopeptide derived from human FSCN1 around the phosphorylation site of Ser39:AS(p-S)LK 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Human fascin is a highly conserved actin-bundling protein. Fascin, encoded by the human homolog for sn (hsn) gene, has been localized to microspikes and stress fibers of cultured cells where it is thought to be involved in the formation of microfilament bundles. It is expressed predominantly in dendritic cells. Lymphoid cells, myeloid cells and plasma cells are negative. However, Reed Sternberg cells in Hodgkin’s lymphoma are positive for fascin staining. Epstein-Barr virus may induce expression of fascin in B cells.