bs-0128R [Primary Antibody]
Rabbit  Anti-PIK3R1  Polyclonal Antibody
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Host: Rabbit

Target Protein: PIK3R1

IR: Immunogen Range:501-600/724

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5295

Swiss Prot: P27986

Source: KLH conjugated synthetic peptide derived from human PI3 kinase p85 subunit alpha:501-600/724 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

Size: 100ul

Concentration: 1mg/ml

Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC=1:100, IF=1:100-500, Flow-Cyt=1μg/Test, ELISA=1:5000-10000

Cross Reactive Species: Human,Mouse,Rat (predicted: Chicken,Dog,Cow,Horse)

For research use only. Not intended for diagnostic or therapeutic use.

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