Host: Rabbit
Target Protein: TLR2
IR: Immunogen Range:701-784/784
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 7097
Swiss Prot: O60603
Source:
KLH conjugated synthetic peptide derived from human TLR2:701-784/784
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq, Jul 2008]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500
Cross Reactive Species: Human,Mouse,Rat (predicted: Chicken,Dog,Pig,Cow,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.