Host: Rabbit

Target Protein: kir 6.1

IR: Immunogen Range:61-160/424

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3764

Swiss Prot: Q15842

Source: KLH conjugated synthetic peptide derived from human kir 6.1:61-160/424 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.