Host: Rabbit

Target Protein: phospho-AKT2 (Ser474)

IR: Immunogen Range:QF(p-S)YS

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 208

Swiss Prot: P31751

Source: KLH conjugated Synthesised phosphopeptide derived from human AKT2 around the phosphorylation site of Ser474:QF(p-S)YS 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]