Host: Rabbit

Target Protein: phospho-CDKN1B (Thr198)

IR: Immunogen Range:RQ(p-T)

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1027

Swiss Prot: P46527

Source: KLH conjugated synthesised phosphopeptide derived from human CDKN1B/P27kip1 around the phosphorylation site of Thr198:RQ(p-T) 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq, Jul 2008]