Host: Rabbit

Target Protein: phospho-HDAC2 (Ser394)

IR: Immunogen Range:ED(p-S)GD

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3066

Swiss Prot: Q92769

Source: KLH conjugated Synthesised phosphopeptide derived from human HDAC2 around the phosphorylation site of Ser394:ED(p-S)GD 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].