Host: Rabbit
Target Protein: phospho-ILK-1 (Ser246)
IR: Immunogen Range:IF(p-S)HP
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3611
Swiss Prot: Q13418
Source: KLH conjugated Synthesised phosphopeptide derived from human ILK-1 around the phosphorylation site of Ser246:IF(p-S)HP
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The ILK protein is important in different biological pathways such as cell adhesion, anchorage-dependent cell cycle progression, oncogenic transformation, and growth factor signaling. The kinase activity of ILK is low in non-activated cells; its activity is stimulated by cell-ECM interactions and by certain growth factors. 3 Negative regulation of ILK is mediated by two phosphatases: PTEN, a tumor suppressor lipid sphatase, and ILKAP, a PP2C protein phosphatase. In tumor cells that do not express PTEN protein, ILK is constitutively active.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Human,Mouse (predicted: Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.