Host: Rabbit

Target Protein: phospho-RPS6KB1 (Ser417)

IR: Immunogen Range:AP(p-S)VL

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6198

Swiss Prot: P23443

Source: KLH conjugated Synthesised phosphopeptide derived from human RPS6KB1 around the phosphorylation site of Ser417:AP(p-S)VL 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].