Host: Rabbit

Target Protein: XRCC3

IR: Immunogen Range:101-180/346

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7517

Swiss Prot: O43542

Source: KLH conjugated synthetic peptide derived from human XRCC3:101-180/346 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C.