Host: Rabbit
Target Protein: BMPR2
IR: Immunogen Range:921-1038/1038
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 659
Swiss Prot: Q13873
Source: KLH conjugated synthetic peptide derived from human BMPR2:921-1038/1038
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Mouse (predicted: Rabbit,Horse,Cow,Pig,Chicken,Rat,Human)
For research use only. Not intended for diagnostic or therapeutic use.