Host: Rabbit

Target Protein: Selenium Binding Protein 1

IR: Immunogen Range:401-472/472

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8991

Swiss Prot: Q13228

Source: KLH conjugated synthetic peptide derived from human SBP1/Selenium Binding Protein 1:401-472/472 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease.