Host: Rabbit

Target Protein: Cullin 1

IR: Immunogen Range:701-776/776

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8454

Swiss Prot: Q13616

Source: KLH conjugated synthetic peptide derived from human Cullin 1:701-776/776 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Cullin 1 may be involved in the degradation of positive cell cycle regulators (for example G1 cyclins in yeast). Human cullin 1 forms a complex with Skp1 and the F box protein Skp2, which is thought to play a role in the ubiquitination of G1 regulatory proteins, as its homolog does in yeast.