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Host: Rabbit
Target Protein: CYP2E1
IR: Immunogen Range:401-493/493
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 1571
Swiss Prot: P05181
Source: KLH conjugated synthetic peptide derived from human CYP2E1:401-493/493
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and biosynthesis. Cytochrome P450 2E1 is induced by ethanol, diabetes and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, and exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
Size: 200ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Human,Rat (predicted: Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
For research use only. Not intended for diagnostic or therapeutic use.