Host: Rabbit
Target Protein: CD105
IR: Immunogen Range:58-110/625
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 2022
Swiss Prot: P17813
Source:
KLH conjugated synthetic peptide derived from human CD105/Endoglin:58-110/625
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Size: 100ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat)
For research use only. Not intended for diagnostic or therapeutic use.