Host: Rabbit
Target Protein: Phospho-MST1 (Thr183)
IR: Immunogen Range:RN(p-T)VI
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 6789
Swiss Prot: Q13043
Source: KLH conjugated Synthesised phosphopeptide derived from human Mst1 around the phosphorylation site of Thr183:RN(p-T)VI
Purification: affinity purified by Protein A
Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background: MST1/STK4 encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
Size: 50ul
Concentration: 1mg/ml
Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
Cross Reactive Species: Human (predicted: Mouse,Rat,Chicken,Cow,Horse,Rabbit)
For research use only. Not intended for diagnostic or therapeutic use.