Host: Rabbit

Target Protein: DBF4B Rabbit pAb

IR: Immunogen Range:41-140/615

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 80174

Swiss Prot: Q8NFT6

Source: KLH conjugated synthetic peptide derived from human DBF4B/ASKL1:41-140/615 

Purification: affinity purified by Protein A

Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background: DBF4B is a regulatory subunit for CDC7, a serine-threonine kinase which links cell cycle regulation to genome duplication. The complex CDC7-DBF4B selectively phosphorylates the MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle. DBF4B localizes to the nucleus and its expression is cell cycle-regulated.