Host: Rabbit

Target Protein: protein C

IR: Immunogen Range:371-460/461

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5624

Swiss Prot: P04070

Source: KLH conjugated synthetic peptide derived from human Vitamin K-dependent protein C heavy chain:371-460/461 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009].