bs-5898R [Primary Antibody]
Rabbit  Anti-HIF3 alpha  Polyclonal Antibody
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Host: Rabbit

Target Protein: HIF3 alpha

IR: Immunogen Range:131-230/669

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 64344

Swiss Prot: Q9Y2N7

Source: KLH conjugated synthetic peptide derived from human HIF3 alpha:131-230/669 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia, transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits, HIF1 alpha, HIF2 alpha, or HIF3 alpha. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.

Size: 100ul

Concentration: 1mg/ml

Applications: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, Flow-Cyt=1μg/Test, ELISA=1:5000-10000

Cross Reactive Species: Human,Mouse,Rat (predicted: Dog,Pig,Cow,Horse)

For research use only. Not intended for diagnostic or therapeutic use.

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