Host: Rabbit

Target Protein: DAL1/EPB41L3

IR: Immunogen Range:131-230/1087

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 23136

Swiss Prot: Q9Y2J2

Source: KLH conjugated synthetic peptide derived from human DAL1/EPB41L3:131-230/1087 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: EPB41L3 is an actin-binding protein originally identified as a molecule whose expression is down-regulated in lung adenocarcinoma. EPB41L3 is a member of the protein 4.1 superfamily, which encompasses structural proteins that play important roles in membrane processes via interactions with actin, spectrin, and the cytoplasmic domains of integral membrane proteins. The gene for EPB41L3 is thought to function as a tumor suppressor and localizes within chromosomal region 18p11.3, which is affected by loss of heterozygosity (LOH) in various adult tumors.