Host: Rabbit

Target Protein: RBBP5

IR: Immunogen Range:131-230/538

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5929

Swiss Prot: Q15291

Source: KLH conjugated synthetic peptide derived from human RBBP5:131-230/538 

Purification: affinity purified by Protein A

Storage: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background: RbBP5, retinoblastoma binding protein 5, belongs to a highly conserved subfamily of WD proteins and contains 6 WD repeats. It binds preferentially to underphosphorylated retinoblastoma protein, which is involved in the control of cell proliferation. RbBP5 is a component of the SET1 complex and of MLL containing complexes. RbBP5 is phosphorylated in response to DNA damage, probably by ATM/ATR.