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Human GADD153 Ready-To-Use IHC Kit (IHC0252H)  
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50T/3200.00元
大包装/询价

产品编号 IHC0252H
英文名称 Human GADD153 Ready-To-Use IHC Kit
中文名称 人GADD153即用型免疫组化试剂盒
别    名 CEBPZ; CHOP; CHOP-10; CHOP10; DDIT3; GADD153; C/EBPzeta; DDIT3 / CHOP  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.

SWISS:
P35638

Gene ID:
1649

产品图片
Immunohistochemical analysis of paraffin embedded human cervical cancer tissue slide using IHC0252H (Human GADD153 IHC Kit).
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