| 产品编号 | IHC0257H |
| 英文名称 | Human Podoplanin Ready-To-Use IHC Kit |
| 中文名称 | 人平足蛋白即用型免疫组化试剂盒 |
| 别 名 | E11; Gp38; OTS-8; Ots8; Pdpn; RANDAM-2; RTI40; T1-alpha; T1a; T1alpha; PDPN_HUMAN; DPN; GP36; Aggrus; Glycoprotein 36 (Gp36); PA2.26 antigen; T1A; 29kDa cytosolic podoplanin intracellular domain; PICD; PSEC0003; PSEC0025 |
| 适用样品基质 | FFPE tissue |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight. Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential. Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue. Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells. Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC. Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm. Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein. SWISS: Q86YL7 Gene ID: 10630 |
| 产品图片 |
Immunohistochemical analysis of paraffin embedded human colon cancer tissue slide using IHC0257H (Human Podoplanin IHC Kit).
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Immunohistochemical analysis of paraffin embedded human tonsil tissue slide using IHC0257H (Human Podoplanin IHC Kit).
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
