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Human CD43 Ready-To-Use IHC Kit (IHC0286H)  
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50T/3200.00元
大包装/询价

产品编号 IHC0286H
英文名称 Human CD43 Ready-To-Use IHC Kit
中文名称 人CD43即用型免疫组化试剂盒
别    名 A630014B01Rik; Cd43; Galgp; Ly-48; Ly48; Spn; CD 43; CD43; CD43 antigen; Galactoglycoprotein; Galactoglycoprotein; GALGP; GPL 115; GPL115; Human gene for sialophorin; Leucocyte sialoglycoprotein; Leucocyte sialoglycoprotein; LEUK_HUMAN; Leukocyte sialogly  
适用样品基质 FFPE tissue
保存条件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells. CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation. By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic. CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors. Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 and ARF deficiency CD43 promotes tumor proliferation and viability. CD43 appears to be an important modulator of leukocyte functions. Diseases associated with CD43 dysfunction include Wiscott-Aldrich Syndrome and Adenoid Basal Cell Carcinoma.

SWISS:
P16150

Gene ID:
6693

产品图片
Immunohistochemical analysis of paraffin embedded human spleen tissue slide using IHC0286H (Human CD43 IHC Kit).
Immunohistochemical analysis of paraffin embedded human tonsil tissue slide using IHC0286H (Human CD43 IHC Kit).
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