| 产品编号 | IHC0190H |
| 英文名称 | Human CD8 Ready-To-Use IHC Kit |
| 中文名称 | 人CD8即用型免疫组化试剂盒 |
| 别 名 | CD8; CD8A; CD8B; CD8B1; LEU2; LY3; LYT3; MAL; p32; P37; CD8 antigen; alpha polypeptide (p32); CD8a; CD8a antigen; CD8a molecule; CD8A_HUMAN; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T cell antigen; T cell antigen Leu2; T cell co receptor; T-cell surface |
| 适用样品基质 | FFPE tissue |
| 保存条件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation. CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules. CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I. CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha. Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation. Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells. Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1. SWISS: P01732 Gene ID: 925 |
| 产品图片 |
Immunohistochemical analysis of paraffin embedded human small intestine tissue slide using IHC0190H (Human CD8 IHC Kit).
Immunohistochemical analysis of paraffin embedded human spleen tissue slide using IHC0190H (Human CD8 IHC Kit).
Immunohistochemical analysis of paraffin embedded human colon cancer tissue slide using IHC0190H (Human CD8 IHC Kit).
Immunohistochemical analysis of paraffin embedded human tonsil tissue slide using IHC0190H (Human CD8 IHC Kit).
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
