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GLP-1R Rabbit pAb (bs-25810R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-25810R
英文名称 GLP-1R Rabbit pAb
中文名称 胰高血糖素样肽-1受体/GLP-1受体抗体
别    名 Glucagon like peptide-1 receptor; GLP 1 R; GLP 1 receptor; GLP 1R; Glp1r; GLP; glp1r; Glucagon like peptide 1 receptor; RATGL1RCP; Glip;MGC138331; GLP-1-R; GLP1R_HUMAN; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R; Precursor.  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse (predicted: Human,Rat)
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 51 kDa
检测分子量
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from rat GLP-1R: 171-270/463 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 GLP1R is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.It has been suggested that this protein influences the feelings of satiety or hunger, sensation of glucose levels, control of glucagon sensitivity of islets, and non insulin-dependent diabetes mellitus. GLP1R is believed to be expressed in human pancreas,lung, brain, stomach, kidney and heart. ESTs have been isolated from skin and kidney libraries.

SWISS:
P43220

Gene ID:
2740

GLP-1R是GLP-1在体内作用的主要靶点,它是一个7次跨膜的G蛋白偶联受体,以cAMP为主要第二信使。GLP-1与GLP-1R结合过程是一个两结构域相互作用的过程,都与胰岛素分泌和糖代谢调节密切相关。
产品图片
25 ug total protein per lane of various lysates (see on figure) probed with GLP-1R polyclonal antibody, unconjugated (bs-25810R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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