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phospho-GluR1(Ser831) Recombinant Rabbit mAb (bsm-62187R)  
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25ul/800.00元
50ul/1400.00元
100ul/2500.00元
大包装/询价
产品编号 bsm-62187R
英文名称 phospho-GluR1(Ser831) Recombinant Rabbit mAb
中文名称 磷酸化谷氨酸受体1重组兔单抗
别    名 GRIA1 | GluR1 (phospho-S831); p-GluR1; phospho-GluR1; p-GRIA1; GRIA1 | GluR1 (phospho-Ser831); GLUH1; GLUR1; GLURA; GluA1; HBGR1; MRD67; MRT76; 2900051M01Rik; Glr-1; Glr1; GluR-A; Glur-1; HIPA1; gluR-K1; GRIA1_HUMAN; GRIA1; AMPA-selective glutamate receptor 1; Glutamate receptor ionotropic, AMPA 1; GRIA1_MOUSE; Glutamate receptor ionotropic, AMPA 1 (GluA1); GRIA1_RAT;   
抗体来源 Rabbit
克隆类型 Recombinant
克 隆 号
交叉反应 Human,Mouse,Rat
产品应用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 102 kDa
检测分子量 102
性    状 Liquid
免 疫 原 A synthesized peptide derived from human GluR1 around the phosphorylation site of S831: PQQ-pS-INE (全长906aa) p831位点需要减掉18aa的信号肽。 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存条件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 AMPA- (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity.

SWISS:
P42261

Gene ID:
2890

NMDAR1又称GluR1 (Glutamate Receptor 1)近年实验研究发现,许多NMDAR拮抗药均具有镇痛活性,表明NMDAR在痛觉传递中具有重要作用,这为新型镇痛药的研究开发提供了新的作用靶点。
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