| 产品编号 | bs-1200R |
| 英文名称 | Omgp |
| 中文名称 | 少突细胞髓磷脂糖蛋白抗体 |
| 别 名 | olyigodendrocyte myelin glycoprotein; OMG; OMGP; Oligodendrocyte-myelin glycoprotein; OMGP_HUMAN. |
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Specific References (1) | bs-1200R has been referenced in 1 publications.
[IF=1.27] Feng, Nianping, et al. "Transplantation of mesenchymal stem cells promotes the functional recovery of the central nervous system following cerebral ischemia by inhibiting myelin‑associated inhibitor expression and neural apoptosis." Experimental and Therapeutic Medicine. IHC-P ; Rat.
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| 研究领域 | 神经生物学 信号转导 细胞凋亡 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human,Mouse,Rat (predicted: Cow) |
| 产品应用 | WB=1:500-2000, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 43kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Omgp: 166-280/440 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Oligodendrocyte myelin glycoprotein (OMG) is a glycosylphosphatidylinositol (GPI)-anchored CNS myelin protein, which is a potent inhibitor of neurite outgrowth in cultured neurons, and contributes significantly to the inhibitory activity associated with CNS myelin. Function: Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. Subunit: Binds to RTN4R. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Tissue Specificity: Oligodendrocytes and myelin of the central nervous system. Post-translational modifications: O-glycosylated in its Ser/Thr-rich repeat domain (Potential). Similarity: Contains 8 LRR (leucine-rich) repeats. Contains 1 LRRNT domain. SWISS: P23515 Gene ID: 4974 Database links: Entrez Gene: 4974 Human Entrez Gene: 100172122 Orangutan Omim: 164345 Human SwissProt: P23515 Human Unigene: 113874 Human OMgp也是髓鞘糖蛋白的一种，在发育期促进轴突生长,成熟期抑制轴突生长.其抑制作用主要由髓鞘来源的抑制分子的共同受体NgR介导,在神经营养因子受体p75NTR以及小GTP酶Rho等信号分子的共同参与下完成. |
| 产品图片 |
Sample: Medulla (Mouse) Lysate at 30 ug
Primary: Anti- Omgp (bs-1200R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 49 kD 
Sample:
Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Lane 3: Rat Cerebrum tissue lysates Lane 4: Rat Cerebellum tissue lysates Primary: Anti-Omgp (bs-1200R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kDa Observed band size: 48 kDa |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
