产品中心-北京博奥森生物技术有限公司

产品编号	bs-1314R
英文名称	Oxytocin R
中文名称	催产素受体(缩宫素受体)抗体
别名	OXYR_HUMAN; Oxytocin receptor; OXTR; OTR1; OT-R; OTR; OT R; OTR 1; OXT R;
	Specific References (12) \| bs-1314R has been referenced in 12 publications. [IF=8.008] Kaho Nakamura. et al. Probing the Spatiotemporal Dynamics of Oxytocin in the Brain Tissue Using a Simple Peptide Alkyne-Tagging Approach. ANAL CHEM. 2022;94(35):11990–11998 IHC ; Mouse. PubMed:36008880 [IF=4.966] Korie Sondgeroth. et al. The Endometrium Contributes to the Differential Contractile Response to Oxytocin of Uterine Tissue from Virgin and Proven Breeder Non-pregnant Rats. 2021 May 14 IHC ; Rat. PubMed:10.1096/fasebj.2021.35.S1.05268 [IF=4.473] Tomoki Kumagai. et al. Oxytocin suppresses CXCL10 production in TNF-α-stimulated human dental pulp stem cells. CELL BIOL INT. 2022 Jul;46(9):1530-1535 ICC, WB ; Human. PubMed:35870165 [IF=4.249] Zoratto, F. et al.Intranasal oxytocin administration promotes emotional contagion and reduces aggression in a mouse model of callousness. (2018) Neuropharmacology.Sep 10;143:250-267. IHC ; mouse. PubMed:30213592 [IF=4.2] Zhang, Fengwei, et al. "Seasonal Expression of Oxytocin and Oxytocin Receptor in the Scented Gland of Male Muskrat (Ondatra zibethicus)." Scientific Reports 7.1 (2017): 16627. WB, IHC-P ; Others. PubMed:29192229 [IF=3.932] Ali II et al. Oxytocin induces intracellular Ca2+ release in cardiac fibroblasts from neonatal rats. Cell Calcium. 2019 Oct 4;84:102099. ICF ; Rat. PubMed:31614270 [IF=2.445] Yuan Z et al. Seasonal expressions of oxytocin and oxytocin receptor in the epididymides in the wild ground squirrels (Citellus Dauricus Brandt). Gen Comp Endocrinol. 2020 Apr 1;289:113391. WB&IHC-P ; Wild ground squirrel. PubMed:31917151 [IF=2.15] Huang, Miaomaio, et al. "The abnormal expression of oxytocin receptors in the uterine junctional zone in women with endometriosis." Reproductive Biology and Endocrinology 15.1 (2017): 1. IHC-P ; Human. PubMed:28049501 [IF=2.136] Liu Q et al. Seasonal expressions of oxytocin and oxytocin receptor in epididymis of the male muskrat (Ondatra zibethicus).(2018) Theriogenology.124:24-31. IHC ; muskrat. PubMed:30336300 [IF=2] Zhang, Ying, et al. "Expression of oxytocin receptors in the uterine junctional zone in women with adenomyosis." Acta Obstetricia et Gynecologica Scandinavica (2015). IHC-P ; Human. PubMed:25627343 [IF=1.974] Raihana Nasrin Ferdousy. et al. Anti-Müllerian hormone stimulates expression of the collagen-specific chaperone 47-kDa heat shock protein in bovine uterine epithelial cells. ANIM SCI J. 2022 Dec;93(1):e13787 IHC ; Bovine. PubMed:36507591 [IF=0] Lim JS et al. Effects of Oxytocin on Cell Proliferation in a Corticotroph Adenoma Cell Line. Endocrinol Metab (Seoul). 2019 Sep;34(3):302-313. IHC-P&ICF ; Mouse&Rat. PubMed:31565883
研究领域	神经生物学生长因子和激素细胞膜受体内分泌病
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human,Mouse,Rat (predicted: Dog,Pig,Cow,Horse)
产品应用	WB=1:500-2000, IHC-P=1:100-500, ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
理论分子量	43kDa
细胞定位	细胞膜
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from mouse oxytocin receptor: 325-388/388 <Cytoplasmic>
亚型	IgG
纯化方法	affinity purified by Protein A
缓冲液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
产品介绍	he protein encoded by this gene belongs to the G-protein coupled receptor family and acts as a receptor for oxytocin. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The oxytocin-oxytocin receptor system plays an important role in the uterus during parturition. [provided by RefSeq, Jul 2008] Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. SWISS: P97926 Gene ID: 18430 Database links: Entrez Gene: 281371 Cow Entrez Gene: 5021 Human Entrez Gene: 18430 Mouse Entrez Gene: 397092 Pig Entrez Gene: 25342 Rat Omim: 167055 Human SwissProt: P56449 Cow SwissProt: P30559 Human SwissProt: P97926 Mouse SwissProt: P32306 Pig SwissProt: P70536 Rat SwissProt: Q28756 Sheep Unigene: 2820 Human Unigene: 333310 Mouse Unigene: 6841 Rat OTR在人的子宫平滑肌细胞膜上有缩宫素受体，缩宫素引起子宫收缩的机制可能是通过激活缩宫素受体而实现的。经研究发现，缩宫素受体在外周组织和中枢神经系统内均有分布。缩宫素与不同组织、细胞上的缩宫素受体结合，通过多种信号转导途径而发挥作用。
产品图片	Sample: Brain (Mouse) Lysate at 40 ug Primary: Anti-Oxytocin R (bs-1314R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 53 kD Sample: Lane 1: Ovary (Mouse) Lysate at 40 ug Lane 2: Cerebrum (Rat) Lysate at 40 ug Lane 3: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-Oxytocin R (bs-1314R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD

	免疫组化常用试剂
	免疫印迹常用试剂
	各种标记二抗

	1、抗体溶解方法
	2、抗体修复方式
	3、常用试剂的配制
	4、免疫组化操作步骤
	5、免疫组化问题解答
	6、Western Blotting 操作步骤
	7、Western Blotting 问题解答
	8、关于肽链的设计
	9、多肽的溶解与保存
	10、酶标抗体效价测定程序

	Alexa Fluor 350 标记
	Alexa Fluor 488 标记
	Alexa Fluor 555 标记
	Alexa Fluor 594 标记
	Alexa Fluor 647 标记
	AP 标记
	APC 标记
	Biotin 标记
	Cy3 标记
	Cy5 标记
	Cy5.5 标记
	Cy7 标记
	FITC 标记
	Gold 标记
	HRP 标记
	PE 标记
	PE-Cy3 标记
	PE-CY5 标记
	PE-CY5.5 标记
	PE-CY7 标记
	RBITC 标记