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Rabbit Anti-Defensin beta 2  antibody (bs-1295R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-1295R
英文名称 Defensin beta 2
中文名称 防御素β2/Defensin β2抗体
别    名 beta Defensin 2; beta-defensin 2; mBD-2; Defensin, beta 2; Defb2; MGC129140; MGC129141; Skin-antimicrobial peptide 1; SAP1; BD-2; BD 2; BD2; Beta 4 Defensin; DEF B2; DEF B4; DEFB 102; DEFB 2; DEFB-2; DEFB 4; DEFB102; DEFB2; DEFB4; Defensin 4 beta; Defensin beta 4; HBD-2; HBD 2; HBD2; SAP 1; SAP1; Skin antimicrobial peptide 1; DFB4A_HUMAN; DEFB4A; DEFB2_MOUSE.  Defensin β2.
Specific References  (1)     |     bs-1295R has been referenced in 1 publications.
[IF=2.215] Karadag Remzi. et al. Effects of Different Doses of Systemic Isotretinoin on Eyes: A Histopathological and Immunohistochemical Study in Rats. Cornea. 2020 May;39(5):621-627  IHC ;  Rat.  
研究领域 微生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse
产品应用 IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 6kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse beta 2 Defensin: 21-71/71 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation. [provided by RefSeq, Jul 2008]

Function:
Has bactericidal activity.

Subcellular Location:
Secreted.

Tissue Specificity:
Kidney, uterus and to a lesser extent in heart.

Similarity:
Belongs to the beta-defensin family.

SWISS:
P82020

Gene ID:
13215

Database links:
Entrez Gene: 13215 Mouse

防御素在人体中广泛分布的,目前已知的α-防御素有6种,研究人员从人体的肾脏、气管、鼻粘膜与唾液中也发现了两种β防御素,在许多器官的上皮细胞与非上皮组织的细胞中发现了β-防御素。
Defensin β2在维持机体天然免疫功能、介导炎症反应以及调节特异性免疫中的作用引起人们的重视,防御素的表达与病原体的入侵紧密相关。
产品图片
Tissue/cell: mouse uterus tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Defensin-beta2/DEFB2/HBD-2 Polyclonal Antibody, Unconjugated(bs-1295R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: mouse kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Defensin-beta2/DEFB2/HBD-2 Polyclonal Antibody, Unconjugated(bs-1295R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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