| 产品编号 | bsm-2022M |
| 英文名称 | HBeAg |
| 中文名称 | 人乙型肝炎e抗原单克隆（包被）抗体 |
| 别 名 | External core antigen; Precore protein; p25; C; HBEAG_HBVD3; |
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Specific References (1) | bsm-2022M has been referenced in 1 publications.
[IF=4.996] Garg, Garima. et al. Presence of entry receptors and viral markers suggest a low level of placental replication of hepatitis B virus in a proportion of pregnant women infected with chronic hepatitis B. SCI REP-UK. 2022 Oct;12(1):1-11 IHC ; Human.
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| 研究领域 | 免疫学 细菌及病毒 |
| 抗体来源 | Mouse |
| 克隆类型 | Monoclonal |
| 克 隆 号 | 2E9 |
| 交叉反应 | HBV |
| 产品应用 | WB=1:500-2000, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 18kDa |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | HBeAg full length protein |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein G |
| 缓 冲 液 | 0.01M PBS(pH7.4) with 0.03% Proclin300 |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful. Function: May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections. Subunit: Homodimerizes. Subcellular Location: Secreted. Host nucleus. Post-translational modifications: Phosphorylated. Cleaved by host furin. Similarity: Belongs to the orthohepadnavirus precore antigen family. SWISS: P0C573 Gene ID: N/A Database links: SwissProt: Q89714 Hepatitis B virus 大量商议 （bsm-2023M，bsm-2022M）可用于双抗夹心。 |
| 产品图片 |
Sample:
Lane 1: Recombinant HBcAg protein, Tag free Lane 2: Recombinant hepatitis B virus e virus like particle protein, His Primary: Anti-HBeAg (bsm-2022M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 18 kDa Observed band size: 25 kDa |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
