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CTNNAL1 Rabbit pAb (bs-1685R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-1685R
英文名称 CTNNAL1 Rabbit pAb
中文名称 粘附分子相关蛋白a1抗体
别    名 ACRP; alpha catenin related protein; alpha CATU; alpha catulin; alpha2 catulin; catenin(cadherin associated protein), alpha like 1; Catenin alpha like protein 1; catenin, alpha like 1; CLLP; Highly similar to ALPHA CATENIN; CTNL1_HUMAN; alpha-catulin; alpha-catenin-related protein; Catenin alpha-like protein 1.  
研究领域 免疫学  细胞膜受体  细胞粘附分子  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Rat (predicted: Human,Mouse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 81 kDa
检测分子量
细胞定位 细胞浆 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CTNNAL1: 151-250/743 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 CTNNAL1 acts as a scaffold in the Rho signalling pathway. May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor. There are three different isoforms.

Function:
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).

Subunit:
Interacts with ARHGEF1.

Subcellular Location:
Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein.

Tissue Specificity:
Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.

Similarity:
Belongs to the vinculin/alpha-catenin family.

SWISS:
Q9UBT7

Gene ID:
8727

Database links:

Entrez Gene: 8727 Human

Omim: 604785 Human

SwissProt: Q9UBT7 Human

Unigene: 58488 Human



产品图片
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CTNNAL1) Polyclonal Antibody, Unconjugated (bs-1685R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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