| 产品编号 | bs-2411R |
| 英文名称 | NKG2A |
| 中文名称 | NK细胞受体2A抗体 |
| 别 名 | KLRC1; C lectin type II protein; CD159 antigen like family member A; CD159A; Killer cell lectin like receptor subfamily C member 1; MGC13374; MGC59791; Natural killer cell lectin; Natural killer group protein 2; NK cell receptor A; NKG2 1/B activating NK receptor; NKG2 A/B activating NK receptor; NKG2 A/B type II integral membrane protein; NKG2; NKG2A_HUMAN; NKG2-A/NKG2-B type II integral membrane protein; NKG2-A/B-activating NK receptor. |
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Specific References (3) | bs-2411R has been referenced in 3 publications.
[IF=15.304] Yao Lei. et al. Phytochemical natural killer cells reprogram tumor microenvironment for potent immunotherapy of solid tumors. BIOMATERIALS. 2022 Jun;:121635 WB, IF, FC ; Mouse.
[IF=6.1] Hall, L. J., et al. "Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor." Mucosal Immunology 6.5 (2013): 1016-1026. other ; Mouse.
[IF=2.37] Zou, Z., et al. "The ANXA1 released from intestinal epithelial cells alleviate DSS-induced colitis by improving NKG2A expression of Natural Killer cells."Biochemical and Biophysical Research Communications (2016). other ; Mouse.
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| 研究领域 | 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Mouse,Rat) |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 28kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse NKG2A: 8-100/244 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008] Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Subunit: Can form disulfide-bonded heterodimer with CD94. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Natural killer cells. Similarity: Contains 1 C-type lectin domain. SWISS: P26715 Gene ID: 3821 Database links: Entrez Gene: 3821 Human Entrez Gene: 16641 Mouse Omim: 161555 Human SwissProt: P26715 Human Unigene: 512576 Human Unigene: 56899 Mouse 自然杀伤细胞活化性受体2A |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
