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Rabbit Anti-TNFSF4 antibody (bs-2463R)
~~~促销,代码SSY221101~~~
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说明书: 50ul  100ul  200ul
50ul/1138.00元
100ul/1880.00元
200ul/2900.00元
大包装/询价

产品编号 bs-2463R
英文名称 TNFSF4
中文名称 肿瘤坏死因子配体超家族成员4抗体
别    名 CD 134L; CD 252; CD134; CD134 ligand; CD134L; CD252; CD252 antigen; glycoprotein 34 kd; Glycoprotein Gp34; GP34; OX-40L; OX40 antigen ligand; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; TNFL4_RAT; Tnfsf4; Tumor necrosis factor (ligand) superfamily member 4; Tumor necrosis factor ligand superfamily member 4; TXGP1.  
研究领域 细胞生物  免疫学  细胞表面分子  淋巴细胞  t-淋巴细胞  细胞因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Rat,  (predicted: Mouse, )
产品应用 WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 22kDa
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from rat TNFSF4: 141-199/199 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq]

Function:
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.

Subunit:
Homotrimer (Probable).

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Detected in T-cell lines, but not in a macrophage cell line.

Similarity:
Belongs to the tumor necrosis factor family.

SWISS:
Q9Z2P3

Gene ID:
89814

Database links:

Entrez Gene: 7292 Human

Entrez Gene: 22164 Mouse

Entrez Gene: 89814 Rat

Omim: 603594 Human

SwissProt: P23510 Human

SwissProt: P43488 Mouse

SwissProt: Q9Z2P3 Rat

Unigene: 181097 Human

Unigene: 4994 Mouse

Unigene: 30043 Rat



产品图片
Sample:
Thymus(Rat) Lysate at 40 ug
Primary: Anti- TNFSF4 (bs-2463R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 22 kD
Observed band size: 33 kD
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