| 产品编号 | bs-2602R |
| 英文名称 | IL10RB Rabbit pAb |
| 中文名称 | 白细胞介素-10受体β抗体 |
| 别 名 | Cd210; CDw210b; CRF2 4; CRF2-4; CRFB4; Cytokine receptor class II; Cytokine receptor class II CRF2 4; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; Cytokine receptor family II member 4; D21S58; D21S66; I10R2_HUMAN; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; IL-10R2; IL-10RB; IL10R2; IL10RB; Interleukin 10 receptor beta; Interleukin-10 receptor subunit 2; Interleukin-10 receptor subunit beta. |
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Specific References (3) | bs-2602R has been referenced in 3 publications.
[IF=4.86] Ohnuma et al. Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes. (2015) J.Immuno. 194:3697-712 FC/FACS,WB ; Mouse.
[IF=3.317] Wang, Jingru. et al. Interleukin-22 attenuates allergic airway inflammation in ovalbumin-induced asthma mouse model. Bmc Pulm Med. 2021 Dec;21(1):1-10 IHC ; Mouse.
[IF=2.66] Lopušná, Katarína, et al. "Murine gammaherpesvirus targets type I IFN receptor but not type III IFN receptor early in infection." Cytokine 83 (2016): 158-170. WB ; Mouse.
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| 研究领域 | 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Human,Mouse,Rat (predicted: Rabbit,Pig,Cow,Dog,Horse) |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 39 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-10RB: 21-120/325 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Interleukin 10 binds specifically and with high affinity to cell surface receptors. Interleukin 10 receptors are members of the class II subgroup of the cytokine receptor superfamily. Mouse and human cDNA clones encoding the ligand binding IL10 receptor have been isolated. The IL10 receptor complex contains two distinct type II cytokine receptor subunits, the ligand binding IL10RA and the IL10RB. The coexpression of both chains is essential for IL10 induced signal transduction. The beta chain serves as an accessory chain essential for the active IL10 receptor complex and necessary for the initiation of signal transdunction. Interleukin 10 receptors are expressed in all cell types that are known to respond to IL10. Subcellular Location: Membrane; Single-pass type I membrane Similarity: Belongs to the type II cytokine receptor family. Contains 2 fibronectin type-III domains. SWISS: Q08334 Gene ID: 3588 Database links: Entrez Gene: 3588 Human Entrez Gene: 16155 Mouse Omim: 123889 Human SwissProt: Q08334 Human SwissProt: Q61190 Mouse Unigene: 654593 Human Unigene: 4154 Mouse |
| 产品图片 |
Sample:
HepG2(Human) Cell Lysate at 30 ug
Lung (Mouse) Lysate at 40 ug
Lung (Rat) Lysate at 40 ug
Primary: Anti-IL10RB (bs-2602R) at 1/200 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 39 kD
Observed band size: 39 kD
Sample:
Lane 1: Spleen (Rat) Lysate at 40 ug
Lane 2: Lung (Rat) Lysate at 40 ug
Lane 3: Small intestine (Rat) Lysate at 40 ug
Lane 4: Lymph node (Rat) Lysate at 40 ug
Primary:
Anti-IL10RB (bs-2602R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 33 kD
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
