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IL17RB Rabbit pAb (bs-2610R)  
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50ul/1180.00元
100ul/1980.00元
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产品编号 bs-2610R
英文名称 IL17RB Rabbit pAb
中文名称 白介素-17B受体抗体
别    名 IL17B Receptor; Interleukin-17 receptor B; IL17RB; IL-17RB; CRL 4; CRL4; Cytokine receptor CRL4; EVI 27; EVI27; IL 17 receptor B; IL 17 receptor homolog 1; IL 17B receptor; IL 17RB; IL 17Rh1; IL17BR; IL17RH1; Interleukin 17 receptor B; Interleukin 17 receptor homolog 1; Interleukin 17 receptor homolog; Interleukin 17B receptor; ecotropic viral integration site 27; interleukin-17 receptor B precursor; MGC5245; I17RB_MOUSE.  
Specific References  (3)     |     bs-2610R has been referenced in 3 publications.
[IF=8.38] Gregory, Lisa G., et al. "IL-25 drives remodelling in allergic airways disease induced by house dust mite." Thorax 68.1 (2013): 82-90.  IHC-P ;  Mouse.  
[IF=3.636] Kawamura Teruhiko. et al. Identification of genes associated with endometrial cell ageing. Mol Hum Reprod. 2021 Feb;27(2):  IHC ;  Human.  
[IF=1.813] Xie Dong-ping. et al. Effect of Electroacupuncture at Zusanli (ST36) on Sepsis Induced by Cecal Ligation Puncture and Its Relevance to Spleen. Evid-Based Compl Alt. 2020;2020:1914031  FC ;  Rat.  
研究领域 免疫学  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human,Mouse,Rat
产品应用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 54 kDa
检测分子量
细胞定位 细胞膜 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL-17RB: 221-320/502 <Cytoplasmic>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq].

Function:
Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.

Subunit:
Interacts with DAZAP2.

Subcellular Location:
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Tissue Specificity:
Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.

Similarity:
Contains 1 SEFIR domain.

SWISS:
Q9NRM6

Gene ID:
55540

Database links:

Entrez Gene: 55540 Human

Omim: 605458 Human

SwissProt: Q9NRM6 Human

Unigene: 5470 Human



产品图片
Sample: Lane 1: Rat Uterus tissue lysates Lane 2: Mouse Uterus tissue lysates Lane 3: Human A549 cell lysates Lane 4: Human HepG2 cell lysates Lane 5: Human HeLa cell lysates Lane 6: Human MCF-7 cell lysates Primary: Anti-IL17RB (bs-2610R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kDa Observed band size: 50 kDa
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-IL17RB (bs-2610R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kD Observed band size: 54 kD
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