扫码关注公众号           扫码咨询技术支持           扫码咨询技术服务
客服热线:400-901-9800  客服QQ:4009019800  技术答疑  技术支持  质量反馈  人才招聘  关于我们  联系我们
产品中心-北京博奥森生物技术有限公司
首页 > 产品中心 > 一抗 > 产品信息
Rabbit Anti-Bone sialoprotein antibody (bs-2668R)
~~~促销,代码SSY221101~~~
订购热线:400-901-9800
订购邮箱:sales@bioss.com.cn
订购QQ:  400-901-9800
技术支持:techsupport@bioss.com.cn
说明书: 50ul  100ul  200ul
50ul/1138.00元
100ul/1880.00元
200ul/2900.00元
大包装/询价

产品编号 bs-2668R
英文名称 Bone sialoprotein
中文名称 骨涎蛋白抗体
别    名 BNSP; Bone sialoprotein II; BSP; BSPII; Cell binding sialoprotein; Integrin binding sialoprotein; SPII; SIAL_HUMAN; Bone sialoprotein 2; BSP II; Cell-binding sialoprotein; Integrin-binding sialoprotein.  
Specific References  (5)     |     bs-2668R has been referenced in 5 publications.
[IF=6.344] Zheng, Han. et al. miR-140-3p enhanced the osteo/odontogenic differentiation of DPSCs via inhibiting KMT5B under hypoxia condition. Int J Oral Sci. 2021 Dec;13(1):1-10  WB ;  Human.  
[IF=3.078] Jilong Zou. et al. Resveratrol Benefits the Lineage Commitment of BMSCs into Osteoblasts via MiR‐320c by Targeting Runx2. 2021 Jan 22  WB ;  Human.  
[IF=4.963] Shi R et al. Analysis of the characteristics and expression profiles of coding and noncoding RNAs of human dental pulp stem cells in hypoxic conditions.Stem Cell Res Ther. 2019 Mar 12;10(1):89.  WB ;  Human.  
[IF=3.23] Potter AS, Potter SS (2015) Molecular Anatomy of Palate Development. PLoS ONE 10(7): e0132662. doi:10.1371  IHC-P ;  Mouse.  
[IF=5.37] Yang, Zhenhua, et al. "Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a β-catenin-dependent manner." Molecular and Cellular Biology (2013): MCB-00456.  Mouse.  
研究领域 生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,  (predicted: Human, )
产品应用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 34kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Bone sialoprotein II: 21-120/317 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]

Function:
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.

Subcellular Location:
Secreted.

Post-translational modifications:
N-glycosylated; glycans consist of sialylated and core-fucosylated bi-, tri- and tetraantennary chains.
Sulfated on either Tyr-320 or Tyr-321 (By similarity).

SWISS:
P21815

Gene ID:
3381

Database links:

Entrez Gene: 3381 Human

Entrez Gene: 15891 Mouse

Entrez Gene: 24477 Rat

Omim: 147563 Human

SwissProt: P21815 Human

SwissProt: Q61711 Mouse

SwissProt: P13839 Rat

Unigene: 518726 Human

Unigene: 4987 Mouse

Unigene: 9721 Rat



产品图片
Sample:
Lane 1: Bone (Mouse) Lysate at 40 ug
Lane 2: Bone (Rat) Lysate at 40 ug
Primary: Anti-Bone sialoprotein (bs-2668R) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 34 kD
Observed band size: 35 kD
版权所有 2019-2022 www.bioss.com.cn 北京博奥森生物技术有限公司
通过国际质量管理体系ISO9001:2008 GB/T19001-2008认证    编号:00115Q211807R1M/1100
京ICP备05066980号-1         京公网安备110107000727号