| 产品编号 | bs-2774R |
| 英文名称 | prox1 |
| 中文名称 | prox-1抗体 |
| 别 名 | Homeobox prospero like protein; Homeobox prospero like protein PROX1; Prospero related homeobox 1;prox-1; PROX 1. |
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Specific References (3) | bs-2774R has been referenced in 3 publications.
[IF=1.918] Gao,et al.High Expression of Prospero-Related Homeobox-1 (PROX1) Is Associated With Poor Prognosis in Patients With Salivary Adenoid Cystic Carcinoma.(2018) Journal of Oral and Maxillofacial Surgery. :. IHC-P ; Human.
[IF=1.61] Usui, Tatsuya, et al. "Establishment of a novel three‐dimensional primary culture model for hippocampal neurogenesis." Physiological Reports 5.12 (2017): e13318. IF(IHC-P) ; Mouse.
[IF=1.347] Teng,et al.Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats.(2018) Experimental Animals. :. WB ; Rat.
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| 研究领域 | 心血管 免疫学 神经生物学 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human,Rat (predicted: Mouse,Dog,Pig,Cow,Horse,Rabbit) |
| 产品应用 | IHC-P=1:100-500, ELISA=1:2000-5000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 81kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human prox-1: 151-250/737 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Prox1 is a prospero-related homeobox gene. Its expression pattern suggests it has a role in a variety of embryonic tissues and may play a fundamental role in early development of the CNS. It may regulate gene expression and the development of postmitotic undifferentiated young neurons. Subcellular Location: Nucleus. Tissue Specificity: Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas. SWISS: Q92786 Gene ID: 5629 Database links: Entrez Gene: 395802 Chicken Entrez Gene: 5629 Human Entrez Gene: 19130 Mouse Entrez Gene: 399348 Xenopus laevis Entrez Gene: 30679 Zebrafish Omim: 601546 Human SwissProt: Q91018 Chicken SwissProt: Q92786 Human SwissProt: P48437 Mouse Unigene: 741808 Human Unigene: 744931 Human Unigene: 132579 Mouse Unigene: 392678 Mouse Unigene: 26557 Rat prox-1主要表达于晶状体、心脏、肝脏、胰腺和神经系统等的非内皮细胞，在成人正常组织、胚胎淋巴管内皮细胞或肿瘤组织的淋巴内皮细胞上也可检测到。移除prox-1基因后，胚胎发育时原始静脉内皮细胞生成淋巴管过程被阻断，表明prox-1是淋巴管生成最基本的调控因子. |
| 产品图片 |
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-prox1 Polyclonal Antibody, Unconjugated(bs-2774R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
