| 产品编号 | bs-3754R |
| 英文名称 | Claudin 6 Rabbit pAb |
| 中文名称 | 紧密连接蛋白6抗体 |
| 别 名 | Claudin6; CLDN 6; CLDN6; Skullin 2; CLD6_HUMAN; Claudin-6; Claudin 6; OTTHUMP00000159248; Skullin-2; Skullin; UNQ757/PRO1488. |
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Specific References (1) | bs-3754R has been referenced in 1 publications.
[IF=1.205] Yosuke Morizawa. et al. Sodium plays an important role in the absorption of intravesical fluid. Luts. 2021 Jan;13(1):177-182 IHC ; Rat.
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| 研究领域 | 肿瘤 细胞生物 免疫学 细胞膜受体 细胞粘附分子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 克 隆 号 | |
| 交叉反应 | Mouse,Rat (predicted: Human,Rabbit,Pig,GuineaPig,Horse) |
| 产品应用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理论分子量 | 23 kDa |
| 检测分子量 | |
| 细胞定位 | 细胞膜 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Claudin 6: 111-220/220 <Extracellular> |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 产品介绍 |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq, Aug 2010] Function: Plays a major role in tight junction-specific obliteration of the intercellular space. Subunit: Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Subcellular Location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the claudin family. SWISS: P56747 Gene ID: 9074 Database links: Entrez Gene: 9074 Human Entrez Gene: 54419 Mouse SwissProt: P56747 Human SwissProt: Q9Z262 Mouse Unigene: 533779 Human Unigene: 485133 Mouse Unigene: 86421 Mouse |
| 产品图片 |
Sample:
Lane 1: Mouse Testis tissue lysates
Lane 2: Rat Testis tissue lysates
Primary: Anti-Claudin 6 (bs-3754R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 23 kDa
Observed band size: 20 kDa
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| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
