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Rabbit Anti-TNFSF15  antibody (bs-5092R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-5092R
英文名称 TNFSF15
中文名称 肿瘤坏死因子配体超家族成员15抗体
别    名 TL1A; TL1 A; TL 1A; TL-1A; tl1; tl1a; tnf ligand related molecule 1; TNF ligand-related molecule 1; tnf superfamily ligand tl1a; TNF15_HUMAN; Tumor necrosis factor ligand superfamily member 15; Vascular endothelial cell growth inhibitor; Vascular endothelial growth inhibitor 192a; Vascular endothelial growth inhibitor; vegi; VEGI192A antibodysecreted form; MGC129934; MGC129935.  
Specific References  (1)     |     bs-5092R has been referenced in 1 publications.
[IF=3.71] Ślebioda, Tomasz Jerzy, et al. "TL1A as a potential local inducer of IL17A Expression in colon mucosa of inflammatory bowel disease patients."Scandinavian Journal of Immunology (2015).  IHC-P ;  Human.  
研究领域 肿瘤  细胞生物  免疫学  转录调节因子  细胞膜受体  血管内皮细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human (predicted: Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,GuineaPig)
产品应用 WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 28kDa
细胞定位 细胞膜 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNFSF15: 161-251/251 <Extracellular>
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.

Function:
Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.

Subunit:
Homotrimer.

Subcellular Location:
Membrane; Single-pass type II membrane protein (Probable). Tumor necrosis factor ligand superfamily member 15, secreted form: Secreted.

Tissue Specificity:
Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.

Similarity:
Belongs to the tumor necrosis factor family.

SWISS:
O95150

Gene ID:
9966

Database links:

Entrez Gene: 9966 Human

Entrez Gene: 326623 Mouse

Entrez Gene: 252878 Rat

Omim: 604052 Human

SwissProt: O95150 Human

SwissProt: Q5UBV8 Mouse

SwissProt: Q8K3Y7 Rat

Unigene: 241382 Human

Unigene: 208152 Mouse

Unigene: 84873 Rat



产品图片
Sample:
bone(mouse) Lysate at 40 ug
Primary: Anti-TNFSF15 (bs-5092R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 28kD
Observed band size: 38 kD
Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-TNFSF15 Polyclonal Antibody, Unconjugated(bs-5092R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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