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Rabbit Anti-ESM1  antibody (bs-3615R)
~~~促销,代码KX240301~~~
~~~促销,代码KX240302~~~
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说明书: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-3615R
英文名称 ESM1
中文名称 内皮细胞特异性分子1抗体
别    名 Endocan; Endothelial cell specific molecule 1; ESM 1; ESM-1; ESM 1 secretory protein; ESM1 secretory protein; ESM1_HUMAN; Endothelial cell-specific molecule 1.  
Specific References  (3)     |     bs-3615R has been referenced in 3 publications.
[IF=8.897] Wu, Qingsi. et al. Targeted delivery of celastrol to glomerular endothelium and podocytes for chronic kidney disease treatment. Nano Res. 2021 Dec;:1-13  IF ;  Mouse.  
[IF=4.522] Zhao H et al. miR‐181a/b‐5p ameliorates inflammatory response in monocrotaline‐induced pulmonary arterial hypertension by targeting endocan. J Cell Physiol. 2019 Oct 21.  IHF&ICF ;  Rat.  
[IF=0] Farahlina Baba. et al. Endocan-microvascular Density in Primary Ovarian Carcinoma. Asian Pac J Cancer P. 2022 Mar 1;23(3):929-935  IHC ;  Human.  
研究领域 心血管  免疫学  细胞粘附分子  内皮细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human (predicted: Horse,Cow,Pig,Rat,Mouse)
产品应用 WB=1:500-2000, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 20kDa
细胞定位 分泌型蛋白 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ESM1: 51-150/184 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 ESM1 is a secreted dermatan sulfate proteoglycan which is predominantly expressed in the endothelial cells in human lung and kidney tissues. Expression of ESM1 is regulated by cytokines. ESM1 may have a role in lung endothelial cell-leukocyte interactions. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.

Function:
May have potent implications in lung endothelial cell-leukocyte interactions.

Subunit:
Monomer.

Subcellular Location:
Secreted. Peroxisome.

Tissue Specificity:
Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.

Post-translational modifications:
May contain intrachain disulfide bonds.

Similarity:
Contains 1 IGFBP N-terminal domain.

SWISS:
Q9NQ30

Gene ID:
11082

Database links:

Entrez Gene: 11082 Human

Entrez Gene: 71690 Mouse

Omim: 601521 Human

SwissProt: Q9NQ30 Human

SwissProt: Q9QYY7 Mouse

Unigene: 129944 Human

Unigene: 38929 Mouse



产品图片
Sample:
Lane 1: Human HUVEC cell lysates
Lane 2: Human U-2 OS cell lysates
Lane 3: Human A549 cell lysates
Primary: Anti-ESM1 (bs-3615R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 43-47 kDa
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