产品编号 | bs-3854R |
英文名称 | GREB1 Rabbit pAb |
中文名称 | 乳腺癌雌激素调控蛋白GREB1抗体 |
别 名 | Gene regulated by estrogen in breast cancer protein; GREB 1; GREB-1; Protein GREB1; KIAA0575; GREB1_HUMAN. |
研究领域 | 肿瘤 细胞生物 免疫学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
克 隆 号 | |
交叉反应 | Human,Mouse |
产品应用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理论分子量 | 216 kDa |
检测分子量 | |
细胞定位 | 细胞膜 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GREB1: 1381-1480/1949 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
缓 冲 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
产品介绍 |
GREB1 is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. GREB1 is expressed in proliferating prostate tissue & prostate cancer and is thought to act as a regulator of hormone-dependent cancer growth in breast and prostate cancers. Its promoter contains putative androgen receptor response elements. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Function: May play a role in estrogen-stimulated cell proliferation. Acts as a regulator of hormone-dependent cancer growth in breast and prostate cancers. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Tissue Specificity: Expressed in proliferating prostatic tissue and prostate cancer. Similarity: Belongs to the GREB1 family. SWISS: Q4ZG55 Gene ID: 9687 Database links: Entrez Gene: 9687 Human Entrez Gene: 268527 Mouse Omim: 611736 Human SwissProt: Q4ZG55 Human SwissProt: Q3UHK3 Mouse Unigene: 467733 Human Unigene: 428062 Mouse GREB1是雌激素受体调节通路中早起反应基因,在乳腺癌、前列腺癌及前列腺增生中发挥着重要的调节作用。 |
产品图片 |
GREB1 Antibody (Cat. bs-3854R) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the GREB1 antibody detected the GREB1 protein (arrow).
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1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |