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GREB1 Rabbit pAb (bs-3854R)  
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50ul/1180.00元
100ul/1980.00元
大包装/询价

产品编号 bs-3854R
英文名称 GREB1 Rabbit pAb
中文名称 乳腺癌雌激素调控蛋白GREB1抗体
别    名 Gene regulated by estrogen in breast cancer protein; GREB 1; GREB-1; Protein GREB1; KIAA0575; GREB1_HUMAN.  
研究领域 肿瘤  细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Human,Mouse
产品应用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 216 kDa
检测分子量
细胞定位 细胞膜 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GREB1: 1381-1480/1949 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 GREB1 is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. GREB1 is expressed in proliferating prostate tissue & prostate cancer and is thought to act as a regulator of hormone-dependent cancer growth in breast and prostate cancers. Its promoter contains putative androgen receptor response elements. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Function:
May play a role in estrogen-stimulated cell proliferation. Acts as a regulator of hormone-dependent cancer growth in breast and prostate cancers.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential).

Tissue Specificity:
Expressed in proliferating prostatic tissue and prostate cancer.

Similarity:
Belongs to the GREB1 family.

SWISS:
Q4ZG55

Gene ID:
9687

Database links:

Entrez Gene: 9687 Human

Entrez Gene: 268527 Mouse

Omim: 611736 Human

SwissProt: Q4ZG55 Human

SwissProt: Q3UHK3 Mouse

Unigene: 467733 Human

Unigene: 428062 Mouse



GREB1是雌激素受体调节通路中早起反应基因,在乳腺癌、前列腺癌及前列腺增生中发挥着重要的调节作用。
产品图片
GREB1 Antibody (Cat. bs-3854R) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the GREB1 antibody detected the GREB1 protein (arrow).
GREB1 Antibody (Cat. bs-3854R) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the GREB1 antibody detected the GREB1 protein (arrow).
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