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GNB2 Rabbit pAb (bs-3942R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包装/询价

产品编号 bs-3942R
英文名称 GNB2 Rabbit pAb
中文名称 G蛋白β2抗体/鸟嘌呤核苷酸结合蛋白β亚基2抗体
别    名 G protein beta 2; G protein beta 2 subunit; G protein subunit beta 2; G protein, beta 2 subunit; Gnb2l1; guanine nucleotide binding protein(G protein), beta polypeptide 2; Guanine nucleotide binding protein beta 2 subunit; Guanine nucleotide binding protein G I G S G T beta 2 subunit 2; Guanine nucleotide binding protein G protein beta polypeptide 2; guanine nucleotide binding protein, beta 2 subunit; RACK1; Receptor for activated C kinase; Receptor of activated protein kinase C 1; signal transducing guanine nucleotide binding regulatory protein beta; Transducin beta chain 2; OTTHUMP00000174601; OTTHUMP00000174602; GBB2_HUMAN.  
研究领域 肿瘤  细胞生物  免疫学  转录调节因子  结合蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
克 隆 号
交叉反应 Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Dog,Horse)
产品应用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理论分子量 37 kDa
检测分子量
细胞定位 细胞浆 
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G protein beta 2: 121-220/340 
亚    型 IgG
纯化方法 affinity purified by Protein A
缓 冲 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
产品介绍 GNB2 belongs to the WD repeat G protein beta family. Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Subunit:
G proteins are composed of 3 units, alpha, beta and gamma. Interacts with ARHGEF18 and RASD2. Interacts with ATXN10.

Subcellular Location:
Cytoplasm, perinuclear region.

Similarity:
Belongs to the WD repeat G protein beta family.
Contains 7 WD repeats.

SWISS:
P62879

Gene ID:
2783

Database links:

Entrez Gene: 2783 Human

Entrez Gene: 14693 Mouse

Entrez Gene: 81667 Rat

Omim: 139390 Human

SwissProt: P62879 Human

SwissProt: P62880 Mouse

SwissProt: P54313 Rat

Unigene: 185172 Human

Unigene: 30141 Mouse

Unigene: 1155 Rat



产品图片
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GNB2) Polyclonal Antibody, Unconjugated (bs-3942R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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